Research presentations
Presenters in bold have given permission to publish their abstracts (links to abstracts will be added soon).
Research presentation session 1 – Thursday 30.11. at 11:00-11:30
| Laura Martin-Diaz | Unveiling the role of a novel actin filament remodelling protein expressed in pancreatic insulin-producing cells |
| Emre Kapucu | Human tripartite cortical network model for temporal assessment of alpha-synuclein aggregation and propagation in Parkinson’s Disease |
| Reetta Nätkin | Transcriptomic and phenotypic characterization of different treatment resistances in castration resistant prostate cancer cells |
Research presentation session 2 – Friday 1.12. at 10:20-11:00
| Yuliya Basikhina | Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila |
| Saana Soppela | Characterization of immune response towards modified Coxsackie B virus-like particle vaccine in a murine model |
| Erdogan Pekcan Erkan | PANORG: a precision oncology approach for colorectal cancer treatment |
| Hatai Jongprasitkul | Tailoring the injectability and printability of photocrosslinkable polypeptides and polysaccharides |
Research presentation session 3 – Friday 1.12. at 13:00-14:15
| Antonio Federico | Systems pharmacology for drug discovery in dermatological diseases |
| Ismaïl Hermelo | Unsupervised clustering reveals non-canonical myeloid cell subsets in brain tumour microenviornment |
| Austin Evans | Non-shrinking photo crosslinking collagen I-hyaluronic acid hydrogels support hiPSC derived cardiac tissue formation and function |
| Annika Länsivaara | Wastewater surveillance of influenza A virus and respiratory syncytial virus epidemics at the national level in Finland |
| Leena-Maija Vanha-aho | MMAR_3485 does not form functional amyloid but contributes to cording morphology in Mycobacterium marinum |
| Hannu Välimäki | Cell-friendly 3D oxygen imaging for microphysiological systems |
| Arjen Gebraad | Bone-on-chips for studying cancer metastasis |
Research presentation session 4 – Friday 1.12. at 14:40-15:10
| Sanna Korpela | Hydrogel platform enabling traction force characterization of retinal pigment epithelium during phagocytosis |
| Rolle Rahikainen | Optical control of covalent protein assembly reveals hierarchy of adhesion protein recruitment |
| Nemanja Milićević | The circadian modulation of melanin biosynthesis by binding to the ROR regulatory motif in the retinal pigment epithelium |
Research presentations in Clinical parallel session – Thursday 30.11. at 14:10-15:00
| Linnea Aitokari | Alanine aminotransferase measurements in children increased 3.9-fold in 1992–2018, while proportion of abnormal results fluctuated without major change |
| Argyro Bizaki-Vallaskangas | A novel association of annexin A13 to secretory otitis media along with studying of genetics of chronic non-suppurative otitis media |
| Rasmus Liukkonen | Predicting failure after revision arthroplasty due to early postoperative prosthetic joint infection of the knee or hip: an external validation of the KLIC-score |
| Aarno Leino | Possibilities of partial HPV genotyping in the Finnish national cervical cancer screening program |
Poster pitches
Presenters in bold have given permission to publish their abstracts (links to abstracts will be added soon).
Poster pitch session 1 – Thursday 30.11. at 9:30-10:00
| Anja Hartewig | The role of non-coding RNAs in the progression of IDH-mutant astrocytomas to grade 4 |
| Suchintak Dash | Monitoring transcription programs in bacteria with synthetic probes |
| Sina Saari | Fibroblasts derived from cold-adapted hare species, Lepus timidus, present distinct metabolic signature associated with adaptive thermogenesis |
| Niila Jouppila | High throughput multiplex assays for establishing pathogen-disease linkage in cohort studies |
| Helka Kaunisto | Effects of gluten consumption on the transcriptomic landscape of Dermatitis Herpetiformis |
| Hana Hien Le | Role of Transglutaminase 2 in enterovirus-infected human intestinal organoids and spatial transcriptomic assessment of mucosal damage in celiac disease |
| Siiri Suominen | Liver-on-a-chip: Development of a 3D liver model utilizing iPSCs and novel microfluidic chip devices |
| Amna Adnan | Effects of bariatric surgery related weight-loss on adipose stromal cell characteristics, metabolism, and immunomodulation capacity in a follow-up study |
| Craig Carlson | Quantifying the dynamic hydrophobicity of carbon black tattoo ink due to ultrasound |
| Sanna Harjula | Genes affecting mycobacterial infection in zebrafish |
| Sana Kari | Drug Repurposing for Glioblastoma: Targeting GPR17 signaling for finding therapeutic opportunities |
Poster pitch session 2 – Thursday 30.11. at 13:00-13:30
| Laura Oksa | Genomic determinants of therapy response in ETV6::RUNX1 leukemia |
| Antti Kiviaho | Spatially resolved transcriptomics points to distinct cell interactions within primary and castration-resistant prostate cancer |
| Laura Vesala | Natural variation of mitochondrial genome alters innate immune responses |
| Vili Lampinen | SpyTag/SpyCatcher display of influenza M2e peptide on norovirus-like particle provides stronger immunization than direct genetic fusion |
| Kaisa Liimatainen | Exploring 3D histology data in virtual reality |
| Annika Ahtiainen | Establishing and assessing temporal interference electrical stimulation in neuronal cultures in vitro |
| Iisa Tujula | Human iPSC glial co-culture chip model for studying neuroinflammation in vitro |
| Christine Gering | Microgels for body on chip applications |
| Joanna Ciantar | The effect of differentially methylated loci between Eastern and Western Finns on gene expression and phenotype |
| Kalle Hokkanen | Instant carcinoma? Examining the possibility of a 2-in-1 hit initiating event in the MLH1 deficient Lynch syndrome tumors using whole-exome sequencing |
Poster pitches in Clinical parallel session – Thursday 30.11. at 15:00-15:30
| Helmi Suominen | Serum IgG antibodies to HPV6 L1, E2, E4, E6 and E7 proteins among children prospectively followed-up for three years |
| Kaisa Taavela | The quality of life of frequently vs. infrequently screened HPV vaccinated women |
| Tiina Koivisto | HPV vaccinations’ association to pregnancy and childbirth prevalence |
| Ivana Kholová | Vasculature, innervation, and collagen of the cardiac conduction system: a morphometrical study |
| Ivana Kholová | Autonomic nerves, vein of marshall, and cardiovascular mortality |
| Leon Csonka | Relation of changes in PEF and FEV1 in exercise challenge in children |
| Eero Numminen | Prolonged persistent genital HPV infections and the future risk of cervical carcinogenesis |
Posters
Presenters in bold have given permission to publish their abstracts (links to abstracts will be added soon).
Poster session 1 – Thursday 30.11. at 10:00-11:00
| Agata Szczodra | In-vitro and in-vivo evaluation of a silicate (1393) and borosilicate (13-93B20) robocasted bioactive glass scaffolds |
| Aliisa Tiihonen | Effect of hypoxia on myeloid immune cells and immunosuppression in diffuse astrocytoma tumors |
| Alina Sillanpää | Extracellular Glycosyltransferase EpsH is Involved in eDNA Accumulation and Antibiotic Sensitivity in Mycobacterial Biofilm |
| Amin Forouzandehmehr | Mechanotransduction in the presence of R403Q hypertrophic cardiomyopathy: a computational study on Piezo1 |
| Amirbabak Sioofy Khojine | Antiviral therapy as a possible treatment for type 1 diabetes |
| Amna Adnan | Effects of Bariatric Surgery Related Weight-Loss on Adipose Stromal Cell Characteristics, Metabolism, and Immunomodulation Capacity in a Follow-Up Study |
| Anja Hartewig | The role of non-coding RNAs in the progression of IDH-mutant astrocytomas to grade 4 |
| Anni Alatalo | Effects of Black Crowberry (Empetrum nigrum subsp. hermaphroditum) supplementation on metabolic and inflammatory adverse effects induced by high-fat diet in a mouse model of obesity |
| Annika Ahtiainen | Assessment of Transplant Organ Quality – OrganAnalytics R2B Project |
| Antti Kallonen | Predictive modelling and exploratory data analysis in the ICU during COVID-19 |
| Craig S. Carlson | Quantifying the dynamic hydrophobicity of carbon black tattoo ink due to ultrasound |
| Daria Kostiniuk | Circulatory hsa-miR-339-5p is associated with later development of non-alcoholic fatty liver disease in the prospective Young Finns Study |
| Ella Lampela | A novel, xeno-/serum free culturing setup for vascularized, engineered muscle bundles |
| Eloise Mikkonen | Common dementia-associated neuropathology in the Tampere Sudden Death Study |
| Emmi Hämäläinen | The workflow for a multicentre randomized controlled trial for metastatic colorectal cancer |
| Erika Aikio | SRSF3 shapes the structure and processing of miR-17-92 cluster |
| Giorgia Migliaccio | Exploring the Role of Innate Immune Memory in Macrophages |
| Hana Hien Le | Role of Transglutaminase 2 in Enterovirus-infected human intestinal organoids and spatial transcriptomic assessment of mucosal damage in celiac disease |
| Harini Wickramaarachchige | Developing vascularized bone tissue on-a-chip for assessing prostate cancer cell extravasation |
| Helka Kaunisto | Effects of gluten consumption on the transcriptomic landscape of Dermatitis Herpetiformis |
| Henna Lappi | iPSC Core Facility – Tampere University |
| Henri Lagerstam | The Milan System Atypia of Undetermined Significance: 5-year performance data |
| Iiro Ahokainen | Theoretical considerations of unsupervised learning with spike-time-dependent-plasticity and winner-take-all circuits |
| Janne Koivisto | Microrheology as a versatile characterization method for 3D hydrogel cell cultures |
| Jenni Kesäniemi | Cancer origin tracing and timing in two high risk prostate cancers using multisample whole genome analysis: potential clinical value |
| Johanna Laakkonen | Towards Blood-Brain Barrier-on-Chip with patient-derived cells to study vascular defects in multiple sclerosis |
| Jonna Alkula | Bacteria-targeting virus-like particle vaccine in prevention of cardiovascular diseases |
| Joona Valtonen | Cellular co-culture rather than 3D environment improves cardiomyocyte functionality in gellan gum-gelatin hydrogel |
| Julia Ventelä | Clustering of acute leukemia in Finland: a nationwide register-based case-control study |
| Kaisla Walls | Cardiac ischemia on-a-chip: The effects of levosimendan and levosimendan metabolite OR-1896 on ischemic human-induced pluripotent stem cell-derived cardiomyocytes |
| Karishma Sajnani | Modelling the prostate tumor microenvironment and its involvement in shaping metastatic potential |
| Kati Rinnekari | Hydrogel screening for 3D vascularization model on-chip |
| Kirsi Rautajoki | Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting |
| Kyriacos Yiannacou | Acoustic Manipulation of Particles in Microfluidic Chips with an Adaptive Controller that Models Acoustic Fields |
| Laura Honkamäki | 3D bioprinted human stem cell derived cornea stromal tissue model with innervation |
| Lena Möbus | Resilient and sensitive human genes – what is behind it? |
| Mai Nguyen | Estimation of fertility potential of cryopreserved ovarian tissue before cancer treatments using micro-CT imaging and machine learning |
| Maiju Junno | The role of nhlrc2 during the early development |
| Mari Niemelä | Simulation of a rotating impeller |
| Marja-Leena Linne | Analysis of network-level properties in brain models with neuron-astrocyte interactions |
| Marja-Leena Linne | Integrating wet-lab data, computational models and tools in EBRAINS digital neuroscience platform for better understanding of the human brain |
| Mart Kroon | Chip development for hydrogel characterization |
| Matthew K. Maasdorp | Investigating the interaction of the immune system with metabolism and the central nervous system in the Drosophila model |
| Matti Aalto | Prediction of patient flow in the emergancy department using explainable AI |
| Nicole Anderton | Calcium carbonate theranostic agent in an ultrasound field |
| Niila Jouppila | High throughput multiplex assays for establishing pathogen-disease linkage in cohort studies |
| Noora Nevala | In vivo imaging approach to study photoreceptor and retinal pigment epithelium cells in zebrafish |
| Pedro A. Moreno-Sánchez | Development of an explainable AI prediction model for ECG-based arrhythmia detection |
| Petri Purola | PhD Thesis: Social and Economic Impact of Glaucoma and Glaucoma Care in Ageing Population |
| Piia Takabe | The role of RNA-binding proteins in platelet biogenesis |
| Puja Sarkar | Effect of extract cellular calcium microenvironment in the formation of GBM spheroid |
| Ropafadzo Mzezewa | Development of a in vitro model for Dravet syndrome using patient hiPSC-derived cortical neurons |
| Saana Seppälä | Developing Astrocytic Glutamate Uptake Model for Neuron-Astrocyte Synapse |
| Saara Marttila | Do epigenetic clocks predict future health outcomes in a middle-aged population, and how do they compare to traditional risk factors of cardiometabolic diseases? |
| Sana Kari | Drug Repurposing for Glioblastoma: Targeting GPR17 signaling for finding therapeutic opportunities |
| Sanna Harjula | Genes affecting mycobacterial infection in zebrafish |
| Sanni Rinne | The influence of EBV antibody levels on oral and genital HPV infection outcome among women |
| Santiago Laguna-Castro | Novel X-ray microtomography imaging method for 3D visualization of prostate architecture |
| Shabnaz Koochakkhani | Alkylaminophenols: a novel third-generation EGFR inhibitor |
| Siiri Suominen | Liver-on-a-chip: Development of a 3D liver model utilizing iPSCs and novel microfluidic chip devices |
| Sina Saari | Fibroblasts derived from cold-adapted hare species, Lepus timidus, present distinct metabolic signature associated with adaptive thermogenesis |
| Stina Gröhn | Hexavalent coronavirus vaccine elicits both humoral and cellular immune responses in mice |
| Suchintak Dash | Monitoring transcription programs in bacteria with synthetic probes |
| Suvi Rintala | Oral microbial transcriptome profiles in OSCCs and the effect of oncogenic HPVs |
| Tiina Lehtola | MKP-1 as a novel anti-inflammatory drug target: cAMP enhancing drugs salbutamol and rolipram promote alternative macrophage activation through MKP-1 |
| Tilman Tietz | Between benefit and harm – the effect of antibiotics-induced mitochondrial dysfunction on innate immune responses |
| Vasyl V. Mykuliak | How vinculin mutant binds vinculin binding sites in talin |
| Zeyad Al-Abdulraheem | Integrative approaches in drug repositioning for lung fibrosis: AI and data analysis |
Poster session 2 – Thursday 30.11. at 15:30-17:00
| Alma Kurki | Ascorbic acid 2-phosphate embedded poly(L-lactide-co-ε-caprolactone) membranes for treating pelvic organ prolapse |
| Alma Yrjänäinen | Barrier-free, open-top microfluidic chip for generating two distinct 3D microvasculatures |
| Anastasiia Yiannacou | In vitro analysis of matrix-filler interactions in Gellan Gum/Bioactive Glass hydrogels |
| Andrey Vinogradov | Exploring kainic acid-induced alterations in tripartite circuit networks |
| Angela Serra | Graph learning for toxicology and chemical safety assessment |
| Annika Ahtiainen | Establishing and assessing temporal interference electrical stimulation in neuronal cultures in vitro. |
| Antti Kiviaho | Spatially resolved transcriptomics points to distinct cell interactions within primary and castration-resistant prostate cancer |
| Antti Vuorisalo | Insufficient EBUS-TBNA specimens. The analysis of criteria and reasons behind the insufficient specimens. |
| Christine Gering | Microgels for body on chip applications |
| Denis Depes / Ivana Kholová | Vasculature, Innervation, and Collagen of the Cardiac Conduction System: a Morphometrical Study |
| Denis Depes / Ivana Kholová | Autonomic Nerves, Vein of Marshall, and Cardiovascular Mortality |
| Eero Numminen | Prolonged persistent genital HPV infections and the future risk of cervical carcinogenesis |
| Elias Kuusela, Neea Pohjamo | Stroke-Heart syndrome on a chip |
| Emilia Siukola | Spatial Transcriptomics of Celiac Disease in different stages of inflammation |
| Emma Raitoharju | Development of non-alcoholic fatty liver is associated with altered DNA methylation profile in blood – A longitudinal multiomic study |
| Hanna Riekki | Prevalence, temporal trends and associated factors of impaired glucose tolerance and type 2 diabetes in Finnish children and adolescents |
| Hanna Sareila | Prevalence, patient perceptions and significance of no-biopsy diagnosis of celiac disease in adults |
| Helmi Suominen | Serum IgG antibodies to HPV6 L1, E2, E4, E6 and E7 proteins among children prospectively followed-up for three years |
| Iida Salonen | Analysis of colorectal cancer microenvironment in the FinCRC cohort |
| Iisa Tujula | Human iPSC glial co-culture chip model for studying neuroinflammation in vitro |
| Ines Baptista | Characterizing bacterial genes with bimodal protein levels |
| Jari Väliaho | Utilizing DBiT-seq technology in prostate cancer spatial omics |
| Jenni Partinen | Rhythmic regulation of photoreceptor outer segment phagocytosis by RPE in zebrafish retina |
| Joanna Ciantar | The effect of differentially methylated loci between Eastern and Western Finns on gene expression and phenotype |
| Juha Määttä | Performance of label-free biosensors as a function of layer thickness |
| Kaisa Liimatainen | Exploring 3D histology data in virtual reality |
| Kaisa Taavela | The quality of life of frequently vs. infrequently screened HPV vaccinated women |
| Kalle Hokkanen | Instant carcinoma? Examining the possibility of a 2-in-1 hit initiating event in the MLH1 deficient Lynch syndrome tumors using whole-exome sequencing |
| Karim Ameziane | Microfluidic Perfusion Chip for Hypoxia Studies |
| Karoliina Salenius | Improving Genomic Variant Detection Efficienty: Insights From Alignment and Variant Caller Comparisons |
| Katriina Vuolteenaho | Meteorin-like protein is a novel factor and potential drug target in osteoarthritis |
| Konsta Kukkonen | Correlates between androgen receptor activation and chromatin accessibility in nonmalignant and malignant prostate epithelial cells |
| Laura A. Saarimäki | Toxicogenomics data for chemical safety assessment: from intrinsic characteristics to translational potential |
| Laura Huhtala | FGFR3-TACC3 fusion protein drives cell migration, lower differentiation state, and aberrant calcium signaling response in glioblastoma |
| Laura Keto | Constructing and optimizing morphologically detailed cerebellar astroglial cell model with Blender-based toolkit CellRemorph |
| Laura Oksa | Genomic determinants of therapy response in ETV6::RUNX1 leukemia |
| Laura Vesala | Natural variation of mitochondrial genome alters innate immune responses |
| Laura Ylä-Outinen | Toxicological Screening of Less-Studied Per- and Polyfluoroalkyl Substances (PFAS) |
| Leevi Halonen | Transient receptor potential (TRP) channel expression in human osteoarthritic chondrocytes —TRPA1 and TRPM8 as potential drug targets |
| Leon Csonka | Relation of changes in PEF and FEV1 in exercise challenge in children |
| Mahmudul Hasan Tanvir | Modelling the interplay between prostate cancer cells and immune cells |
| Markus Hannula | Validation of the X-ray microtomography in the small intestine biopsy analysis |
| Mauro Scaravilli | High Mobility Group A1 (HMGA1) is a non-canonical RNA-binding protein with regulatory functions in pluripotent stem cells |
| Michele Fratello | From Molecules to Mechanisms: An Interactive Tool for Knowledge Discovery |
| Minne Jartti | Structure–function informed design of virus-like particle-based rhinovirus vaccine |
| Muktesh Athale | Context-specific interactomics through targeted covalent conjugation of BirA* revealed the possible association of tensin3 with talin |
| Nea Koskela | Risk factors associated with IgG seropersistence to C. trachomatis and M. genitalium among heterosexual couples |
| Olga Albó | Neutrophils in dermatitis herpetiformis and celiac disease |
| Pedro A. Moreno-Sánchez | Explainable AI analysis of a prediction model for detecting premature atrial and ventricular complexes |
| Rahul Jagadeesan | Transcription dynamics in bacterial operons during genome-wide stresses. |
| Saara Tillqvist | Musculoskeletal symptoms are frequent among coeliac disease patients on gluten-free diet |
| Satu Jäntti | Seizures-on-chip to model human epilepsies |
| Sonja Harjuntausta | Corneal epithelial commitment during early differentiation of induced pluripotent stem cells |
| Sonja Mäntylä | Genetic features driving the development of both epithelioid GB and PLNTY in one patient: A case report |
| Stefanus Wirdatmadja | Wireless carbon-based electrochemical dopamine sensor brain implant |
| Susanna Harju & Susanna Kaksonen | Functional characterization of human peripheral neurons and applications in target tissue innervation |
| Susanna Valanne | Ubiquitin-conjugating E2-enzyme Effete controls hemocyte activation in Drosophila melanogaster |
| Tanja Hyvärinen | Assessment of microglia phenotype in multiple sclerosis using patient-derived induced pluripotent stem cells |
| Tiina Koivisto | HPV vaccinations’ association to pregnancy and childbirth prevalence |
| Tomi Ryynänen | Development of 3D in vitro microelectrode arrays for 3D cell models |
| Trina Chen | Systematic and morphological assessment of the ascending aorta undergoing surgery for dissection and dilation: Application of Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology consensus statement in the tertiary care hospital in Finland |
| Valeriia Dotsenko | Integrated Omics Analysis Reveals Insights into Celiac Disease Pathogenesis |
| Venla Harju | Uptake of clinically relevant human platelet secreted extracellular vesicles into human induced pluripotent stem cell derived neurons in hypoxic conditions |
| Viivi Karema-Jokinen | Reduced currents and altered localization of calcium channel CaV1.3 in retinal pigment epithelium derived from patients with age-related macular degeneration |
| Vili Lampinen | SpyTag/SpyCatcher display of influenza M2e peptide on norovirus-like particle provides stronger immunization than direct genetic fusion |
| Wiljami Ventilä | Implementations for data acquisition and analysis in a dopamine sensing brain implant: a review |