14th NorPEN meeting 16–18 November, 2022
Data-driven decision making in healthcare and health promotion
Tampere University, Main building, Auditorium A1, Kalevantie 4, Tampere, Finland
Wednesday 16 November, 2022, Pre-conference workshop
Teachers: Jari Haukka and Tommi Härkänen
13:00–17:00 Workshop on multiple time scales – useful approach in pharmacoepidemiology (own laptops )
In cohort studies with time-to-event outcomes we are usually interested in more than one time-scale. Such time-scales are e.g. time after start of treatment, time after stopping treatment, age, calendar time, and time since diagnosis. Cox’s proportional hazards models allow only one time scale, but with Poisson regression models two or more time-scales can be analyzed simultaneously. This workshop provides an introduction to understand and analyze multiple time scales. Hands-on practicals provide participants with working R-language scripts. Basic knowledge of the R language is essential for participants.
Theoretical session + hands on practicals with data
Pre-reading materials will be provided for the participants
Working knowledge of R language required for practicals
17:15-18:30 Executive Committee meeting (for representatives and substitutes)
Social program:
19:00 Welcome reception at the Tampere City House, Keskustori 10, Tampere
20:00 PhD student dinner at Sauna Restaurant Kuuma, Laukontori 21, Tampere
Thursday 17 November, 2022, NorPEN meeting
09:00–09:15 Welcome words, Tapio Visakorpi, vice dean, Tampere University (FI)
09:15–12:00 Keynote lectures, chair Jari Haukka, university lecturer, University of Helsinki (FI)
9:15–10:00 Disease prevention in non-communicable diseases and mental disorders, Mika Kivimäki, professor, University College, London (UK)
10:00–10:45 Challenges and opportunities of multi-country, multi-database pharmacoepidemiologic studies, Olaf Klungel, professor, Utrecht University (NL)
10:45–11:15 Coffee
11:15–12:15 Oral presentations, chair Leena Saastamoinen, research manager, Social Insurance Institution (FI)
12:15–13:15 Lunch
13:15–14:30 Session 1 Topic: Prevention interventions in reproductive health, chair Maarit Leinonen, research manager, Finnish Institute for Health and Welfare (FI)
13:15-13:40 Tiina Jääskeläinen, university lecturer, University of Helsinki (FI): Preeclampsia as a risk factor for cardiovascular disease after pregnancy
13:40-14:05 Hedvig Nordeng, professor, University of Oslo (NO): Risk of childhood cancer after maternal exposure to medications
14:05-14:30 Elena Toffol, postdoctoral researcher, University of Helsinki (FI): Hormonal contraception and mental health: a register-based, nested case-control study from Finland
14:30–15:00 Coffee
15:00–15:40 Session 2 Topic: Methodological issues in cancer pharmacoepidemiology, chair Sirpa Hartikainen, professor, University of Eastern Finland (FI)
15:00–15:40 Teemu Murtola, professor, Tampere University (FI): How to avoid common pitfalls in pharmacoepidemiological cancer research?
15:40–17:00 Pharmacoepi slam
15:40–16:45 Slam
16:45–17:00 Q&A
Social program:
19:00 Congress Dinner, Puistotornin juhlasali, Hämeenpuisto 28, Tampere
Friday 18 November, 2022, NorPEN meeting
09:00–10:20 Session 3 Topic: Open and shareable methods for drug use modelling from register-based data, chair Heidi Taipale, assistant professor, Karolinska Institutet (SE), University of Eastern Finland (FI)
9:00–9:20 Laura Pazzagli, statistician, Karolinska Institutet (SE): Exposure definition in pharmacoepidemiology – example of an open source software for treatment episodes construction
9:20–9:40 Henrik Støvring, associate professor, Århus University (DK): Estimation of prescription durations using the reverse Waiting Time Distribution – a general, maximum likelihood-based method
9:40–10:00 Maurizio Sessa, assistant professor (tenure), University of Copenhagen (DK): Sessa empirical estimator: rationale, performance, and applications in real-world data
10:00–10:20 Pia Vattulainen, biostatistician, Niuvanniemi Hospital (FI): From Prescriptions to Drug Use Periods (PRE2DUP) R-version
10:20–10:40 Coffee
10:40–11:20 Oral presentations (10 min each), chair Mika Gissler, research professor, Finnish Institute for Health and Welfare (FI)
11:20–12:40 Session 4 Topic: Methodological issues in pharmacovigilance, chair Miia Artama, professor (tenure), Tampere University, Finnish Institute for Health and Welfare (FI)
11:20–12:00 Joan Morris, professor of medical statistics, St Georges´s University of London (UK): Basic methods to combine pharmacoepidemiological data analyzed at different countries
12:00–12:40 Xavier Kurz, head, Data Analytics Workstream European Medicines Agency (NL): Big Health Care Data
12:40–13:00 Closing words and introduction of new Executive Committee and next NorPEN meeting in 2023, History and future of NorPEN, Sirpa Hartikainen, professor, University of Eastern Finland (FI)
13:00-14:00 Lunch and departure