Programme
Thursday 12 December 2024 (location: auditorium A1, 2nd floor)
8:30-10:00
1st morning session: Burden of Hemorrhagic Stroke
Frösén J: Opening words
Rufenacht D: Personalized medicine for unruptured aneurysms
Bijlenga P: Aneurysm treatment in the elderly
Räisänen S: Aneurysms in young adults and children
Halmela A: AVMs in young and children
Patient organization: View of the patient
10:00-10:30
Coffee and exhibition, Portrait foyer, 2nd floor
10:30-12:00
2nd morning session: Etiology of aneurysms formation and rupture
Tutino V: Distinct RNA Expression Signatures of Ischemic Stroke Etiology in a Large, Multi-Center Clot Transcriptome Dataset
Patrakka O: Dental Pathogens in Thrombus Aspirates from Ischemic Stroke Patients
Morgan J: Development of AneuScreen+TM, a Novel Blood-Based Gene Expression Diagnostic to Assess Risk of Intracranial Aneurysm Rupture
Pyysalo M: Dental infections in the formation, growth, and rupture of intracranial aneurysms
Tobe Y: Comparative Analysis of Collagen Structure and Smooth Muscle Cell Actin Density in Human Intracranial Aneurysms
Panel discussion
12:00-13:00
Lunch, YO Restaurant, 2nd floor
Company time
13:00-14:30
1st afternoon session: Computational fluid dynamics for cerebrovascular diseases
Tutino V: Spatial Transcriptomics of Remodeling Brain Arteries Reveals Potential Molecular Signals for Dystrophic vs Eutrophic Responses to Flow
Cebral J: Flow-driven remodeling of aneurysms
Yanagisawa K: A pipeline using point cloud representation for rapid hemodynamics analysis
Liao J: Impact of point cloud preprocessing on Physics-Informed Neural Networks (PINNs) for 3D cerebrovascular hemodynamic prediction in limited patient data scenario
Janiga G: Validation of computational fluid dynamics for clinical use
Stahl J: Transverse sinus stenosis hemodynamics: Flow complexities at the temporal bone
14:30-15:00
Coffee and exhibition, Portrait foyer, 2nd floor
15:00-16:45
2nd afternoon session: Radiomics for cerebrovascular diseases
TBA: Radiomics in cerebrovascular diseases
Hirsch S: Automated vessel segmentation
Yin L: Advancing Cerebrovascular Lesion Management with AI: A System for Multimodality Vessel and Aneurysm Segmentation
Poppenberg K: Longitudinal Assessment of Vessel Wall Radiomics and Luminal Blood Flow During Evaluation of Intracranial Atherosclerotic Plaques
Abhdurakhmonov M: Comprehensive analysis of cerebrovascular vasa vasorum specimen
TBA: Vessel wall imaging for intracranial aneurysms
Panel discussion
19:00
City of Tampere reception at the Old City Hall (address: Keskustori 10)
Friday 13 December 2024 (location: auditorium A1, 2nd floor)
8:30-10:00
1st morning session: What's new in hemorrhagic stroke?
Frösen J – Introduction & Epidemiology of hemorrhagic stroke
Stribian D: Intracerebral hemorrhage as a cause of mortality and morbidity
ENRICH trial investigators: When and how should we perform surgical evacuation of ICH?
Kellner C: Minimally invasive endoscopic ICH surgery (SCUBA)
Darsaut T: Final results of ISAT-2 trial (Surgery vs EVT for ruptured non-ISAT aneurysms)
Panel discussion
10:00-10:30
Coffee and exhibition, Portrait foyer, 2nd floor
10:30-12:00
2nd morning session: Advances in aneurysm surgery
TBA: Flow diversion for aneurysms – the long term results
Taussky P: Flow diversion for aneurysms – the long term results
Boogarts J: Advantages of being a hybrid traing vascular neurosurgeon
Radovanovic I: Evolution and current trends in minimally invasive surgery for intracranial aneurysms
Bijlenga P: Mixed Reality and Intra-Operative Angiography for Enhanced Precision in Cerebrovascular Surgery
Darsaut T: The Comprehensive Aneurysm Management (CAM) trial on unruptured aneurysms
Panel discussion
12:00-13:00
Lunch, YO Restaurant, 2nd floor
Company time
13:00-14:30
1st afternoon session: Personalized treatment for aneurysms and AVMs
Bijlenga P: Introduction
Fujimura S: Machine learning-based prediction of framing coils for coil embolization in intracranial aneurysms
Koshiba T: End-to-End Deep Learning System for Automated Detection and First Coil Prediction in Coil Embolization of Cerebral Aneurysms
Uchida T: Simulation construction to Reproduce Particle Emboization Using the Macroscopic Particle Model (MPM)
Alaraj A: Should AVM treatment be personalized ? Role of flow dynamics as Biomarker
Panel discussion
14:30-15:00
Coffee and exhibition, Portrait foyer, 2nd floor
15:00-16:45
2nd afternoon session: Advances in AVM treatment
Järvelin P: Selection of optimal treatment modality according to Spetzler-Ponce grading
Arnberg-Sandor: Embolization of brain AVMs – current state of the art
TBA: Augmented reality in brain AVM surgery
Frösen J: Anti-angiogenic therapy for brain AVMs
Keränen S: Role of inflammation and microbiome in the pathology of brain AVMs
Darsaut T: The Treatment of Brain AVMs Study (TOBAS): Two RCTs and multiple registries
Panel discussion
18:30
Conference Dinner & Aneurysm challenge, Tampere Hall, room Maestro (address: Yliopistonkatu 55)
Saturday 14 December 2024 (location: auditorium D11, 0 floor)
8:30-10:00
1st morning session: Semantic networks & systems biology approach
Hirsch: Introduction
Tarkiainen J: Accuracy of current risk factor score to predict the unstable clinical course of intracranial aneurysms
van Gils / Clinical decision support tools
Cebral J: Use of machine learning to identify factors associated with aneurysms rupture
Deluchi / Hirsch: Towards Reliable IA disease modelling: Integrating Multicentric Registry Data and Clinical Expertise
Panel discussion
10:00-10:30
Coffee break, Alakuppila lobby, 0 floor
10:30-12:00
2nd morning session: Genotype, Phenotype, Exposome
Janiga: Introduction
Kamatani Y: The BRAIN-HEDGE study to elucidate the genetics of hemodynamics in Japanese population
Yan C: Geometry and Pattern Analysis of Cerebral Major Arteries in a Large-Scale Japanese MRA study
Laukka D: Association of systemic atherosclerosis and intracranial aneurysms
Pyysalo / Frösen: Microbiome as a driver of aneurysmatic disease
Panel discussion
12:00-13:00
Lunch, YO Restaurant, 2nd floor
13:00-14:30
1st afternoon session: Organ on chip
Cebral: Introduction
Ohta M: The effect of OSI on endothelial cells
Mansur A: Human-derived AVM cell culture model & drug therapy testing
Keränen S: In vitro studies on the impact of bacteria antigens on KRAS mutated endothelial cells
Narkilahti S: Organ on chip models for cerebrovascular disease
Panel discussion
14:30-15:00
Coffee break, Alakuppila lobby, 0 floor
15:00-16:45
2nd afternoon session
Workshop: Current state and Steps towards personalized treatment of brain aneurysms and AVMs
All conference attendees are welcome to this workshop that will draft an outline for a consensus paper on the topic based on the presentations of the ICS2024 meeting.