Programme

Thursday 12 December 2024 (location: auditorium A1, 2nd floor)

8:30-10:00

1st morning session: Burden of Hemorrhagic Stroke

Frösén J: Opening words

Rufenacht D: Personalized medicine for unruptured aneurysms

Bijlenga P: Aneurysm treatment in the elderly

Räisänen S: Aneurysms in young adults and children

Halmela A: AVMs in young and children

Patient organization: View of the patient

10:00-10:30

Coffee and exhibition, Main Auditorium foyer, 2nd floor

10:30-12:00

2nd morning session: Etiology of aneurysms formation and rupture

Tutino V: Distinct RNA Expression Signatures of Ischemic Stroke Etiology in a Large, Multi-Center Clot Transcriptome Dataset

Patrakka O: Dental Pathogens in Thrombus Aspirates from Ischemic Stroke Patients

Morgan J: Development of AneuScreen+TM, a Novel Blood-Based Gene Expression Diagnostic to Assess Risk of Intracranial Aneurysm Rupture

Pyysalo M: Dental infections in the formation, growth, and rupture of intracranial aneurysms

Tobe Y: Comparative Analysis of Collagen Structure and Smooth Muscle Cell Actin Density in Human Intracranial Aneurysms

Panel discussion

12:00-13:00

Lunch, YO Restaurant, 2nd floor

Company time

13:00-14:30

1st afternoon session: Computational fluid dynamics for cerebrovascular diseases

Tutino V: Spatial Transcriptomics of Remodeling Brain Arteries Reveals Potential Molecular Signals for Dystrophic vs Eutrophic Responses to Flow

Cebral J: Flow-driven remodeling of aneurysms

Yanagisawa K: A pipeline using point cloud representation for rapid hemodynamics analysis

Liao J: Impact of point cloud preprocessing on Physics-Informed Neural Networks (PINNs) for 3D cerebrovascular hemodynamic prediction in limited patient data scenario

Janiga G: Validation of computational fluid dynamics for clinical use

Stahl J: Transverse sinus stenosis hemodynamics: Flow complexities at the temporal bone

14:30-15:00

Coffee and exhibition, Main Auditorium foyer, 2nd floor

15:00-16:45

2nd afternoon session: Radiomics for cerebrovascular diseases

TBA: Radiomics in cerebrovascular diseases

Hirsch S: Automated vessel segmentation

Yin L: Advancing Cerebrovascular Lesion Management with AI: A System for Multimodality Vessel and Aneurysm Segmentation

Poppenberg K: Longitudinal Assessment of Vessel Wall Radiomics and Luminal Blood Flow During Evaluation of Intracranial Atherosclerotic Plaques

Abhdurakhmonov M: Comprehensive analysis of cerebrovascular vasa vasorum specimen

TBA: Vessel wall imaging for intracranial aneurysms

Panel discussion

19:00

City of Tampere reception at the Old City Hall (address: Keskustori 10)

Friday 13 December 2024 (location: auditorium A1, 2nd floor)

8:30-10:00

1st morning session: What's new in hemorrhagic stroke?

Frösen J – Introduction & Epidemiology of hemorrhagic stroke

Stribian D: Intracerebral hemorrhage as a cause of mortality and morbidity

ENRICH trial investigators: When and how should we perform surgical evacuation of ICH?

Kellner C: Minimally invasive endoscopic ICH surgery (SCUBA)

Darsaut T: Final results of ISAT-2 trial (Surgery vs EVT for ruptured non-ISAT aneurysms)

Panel discussion

10:00-10:30

Coffee and exhibition, Main Auditorium foyer, 2nd floor

10:30-12:00

2nd morning session: Advances in aneurysm surgery

TBA: Flow diversion for aneurysms – the long term results

Taussky P: Flow diversion for aneurysms – the long term results

Boogarts J: Advantages of being a hybrid traing vascular neurosurgeon

Radovanovic I: Evolution and current trends in minimally invasive surgery for intracranial aneurysms

Bijlenga P: Mixed Reality and Intra-Operative Angiography for Enhanced Precision in Cerebrovascular Surgery

Darsaut T: The Comprehensive Aneurysm Management (CAM) trial on unruptured aneurysms

Panel discussion

12:00-13:00

Lunch, YO Restaurant, 2nd floor

Company time

13:00-14:30

1st afternoon session: Personalized treatment for aneurysms and AVMs

Bijlenga P: Introduction

Fujimura S: Machine learning-based prediction of framing coils for coil embolization in intracranial aneurysms

Koshiba T: End-to-End Deep Learning System for Automated Detection and First Coil Prediction in Coil Embolization of Cerebral Aneurysms

Uchida T: Simulation construction to Reproduce Particle Emboization Using the Macroscopic Particle Model (MPM)

Alaraj A: Should AVM treatment be personalized ? Role of flow dynamics as Biomarker

Panel discussion

14:30-15:00

Coffee and exhibition, Main Auditorium foyer, 2nd floor

15:00-16:45

2nd afternoon session: Advances in AVM treatment

Järvelin P: Selection of optimal treatment modality according to Spetzler-Ponce grading

Arnberg-Sandor: Embolization of brain AVMs – current state of the art

TBA: Augmented reality in brain AVM surgery

Frösen J: Anti-angiogenic therapy for brain AVMs

Keränen S: Role of inflammation and microbiome in the pathology of brain AVMs

Darsaut T: The Treatment of Brain AVMs Study (TOBAS): Two RCTs and multiple registries

Panel discussion

18:30

Conference Dinner & Aneurysm challenge, Tampere Hall (address: Yliopistonkatu 55)

Saturday 14 December 2024 (location: auditorium D11, 0 floor)

8:30-10:00

1st morning session: Semantic networks & systems biology approach

Hirsch: Introduction

Tarkiainen J: Accuracy of current risk factor score to predict the unstable clinical course of intracranial aneurysms

van Gils / Clinical decision support tools

Cebral J: Use of machine learning to identify factors associated with aneurysms rupture

Deluchi / Hirsch: Towards Reliable IA disease modelling: Integrating Multicentric Registry Data and Clinical Expertise

Panel discussion

10:00-10:30

Coffee break, Alakuppila lobby, 0 floor

10:30-12:00

2nd morning session: Genotype, Phenotype, Exposome

Janiga: Introduction

Kamatani Y: The BRAIN-HEDGE study to elucidate the genetics of hemodynamics in Japanese population

Yan C: Geometry and Pattern Analysis of Cerebral Major Arteries in a Large-Scale Japanese MRA study

Laukka D: Association of systemic atherosclerosis and intracranial aneurysms

Pyysalo / Frösen: Microbiome as a driver of aneurysmatic disease

Panel discussion

12:00-13:00

Lunch, YO Restaurant, 2nd floor

13:00-14:30

1st afternoon session: Organ on chip

Cebral: Introduction

Ohta M: The effect of OSI on endothelial cells

Mansur A: Human-derived AVM cell culture model & drug therapy testing

Keränen S: In vitro studies on the impact of bacteria antigens on KRAS mutated endothelial cells

Narkilahti S: Organ on chip models for cerebrovascular disease

Panel discussion

14:30-15:00

Coffee break, Alakuppila lobby, 0 floor

15:00-16:45

2nd afternoon session

Workshop: Current state and Steps towards personalized treatment of brain aneurysms and AVMs

All conference attendees are welcome to this workshop that will draft an outline for a consensus paper on the topic based on the presentations of the ICS2024 meeting.

18:30

Fairwell dinner, restaurant Koski (address: Kirkkokatu 10)